Commandeering a biological pathway using aptamer-derived molecular adaptors
نویسندگان
چکیده
منابع مشابه
Commandeering a biological pathway using aptamer-derived molecular adaptors
Induction of molecular proximity can mediate a discrete functional response in biological systems. Therefore, creating new and specific connectivity between non-interacting proteins is a means of imposing rational control over biological processes. According to this principle, here we use composite RNA aptamers to generate molecular adaptors that link various 'target' molecules to a common 'uti...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2010
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/gkp1207